Extracoronary Calcification Linked to Increased Risk of Heart Failure with Preserved Ejection Fraction

WASHINGTON, April 14, 2025 (APMnews) – The presence of extracoronary calcification—defined as calcification of the thoracic aorta, left-sided heart valves, and aortic root—is associated with an increased risk of heart failure, particularly heart failure with preserved ejection fraction (HFpEF), according to the MESA study published in JACC: Heart Failure.